THE
TECHNOLOGY

TTop is a modular, versatile and user-friendly Micro-physiological platform

 

that guarantees more predictive results than conventional cell culture technologies, replicating complex human pathophysiological

conditions and enabling a  fast integration in the biological research environment without complex handling requirements or specialized

skills for the users.

THE

cartridge

THE KEY FEATURES

OF TTOP:

a cartridge-based design,

both suitable for well-established studies (cell seeding on membranes), and for cutting-edge culture methodologies (use of 3D structures, scaffolds or tissue biopsies, native tissues, …).

compartmentalized cultures/co-cultures,

recapitulating complex interactions between different cell types, mimicking the in-vivo local environment.

real time imaging of both sample sides,

allowing to evaluate dynamics of growth and differentiation of the biological sample, but also absorption, distribution, metabolism, or excretion of selected drugs.

CONTINUITY WITH STANDARD LABORATORY APPROACHES,

Allowing to easily translate standard in vitro models, without introducing complex handling/technology requirements

 

easy recovery of the biological sample without any morphological damage,

to perform post treatment analysis. This new feature can represent a paradigm shift in the field, allowing to access directly to the biological sample, enabling a more accurate inspection and further assessment of the unknown effects of drugs, nutraceutics, chemicals, pathogens, or environmental toxins.

 

A MODULAR DESIGN,

allowing to host the cartridge in different modules, each designed to replicate specific pathophysiological conditions.  

 

INTEGRATED BIOSENSORS,

allowing to monitor and control in real-time the experimental process and to extract quantitative data about cell growth and differentiation.  

 

LEARN ABOUT HOW WE APPLY THIS

TECHNOLOGY

easy to use systems.

Our products are easy to use, for everyone, with our plug and play technology.